How long can you take leflunomide? However, keep in mind, if you were gaining any benefit from leflunomide, it will usually take at least 6 weeks to lose it. If you are stopping because of more severe side effects, your doctor may recommend a medication regimen to clear the leflunomide out of your system, as it can otherwise remain in you for 1-2 years. What is methotrexate lung? Methotrexate is the folic acid analogue drug that used in various dermatological disorders, especially in psoriasis. Cutaneous and systemic side effects can be seen during methotrexate treatment. Methotrexate is a toxic drug to the lungs, but this condition is not common. Does hydroxychloroquine make you gain weight? Abnormal weight gain is a side effect of long-term doxycycline and hydroxychloroquine treatment. Gut microbiota modifications at the phylum level could play an instrumental role in this effect. Does leflunomide cause diarrhea? The most common adverse effects of leflunomide in clinical trials were gastrointestinal symptoms, especially diarrhea. Diarrhea was usually transient and generally seen during the first few weeks of treatment[6,7].
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