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How often should you get a b12 shot? The usual dose for pernicious anemia-associated vitamin B12 deficiency is 100 mcg given as an injection into the muscle or under the skin once daily for 6-7 days. Then the dose may be given every other day for 7 doses followed by every 3-4 days for around 3 weeks. Then, 100 mcg should be injected every month for life. What is the side effect of vitamin b12? Common side effects of vitamin B12 : Headache. Itching. Swelling. Nervousness and anxiousness.
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