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How long does it take thyroid medication to get out of your system? Levothyroxine has a half-life of roughly 7 days. This is the time it takes the body to reduce plasma levels by half. This means it will take about 4 to 5 weeks before the concentration is too low to have any effect. How can I naturally balance my thyroid? Low thyroid hormones can affect your body's vitamin B-12 levels. Taking a vitamin B-12 supplement may help you repair some of the damage your hypothyroidism caused. You can add more B vitamins to your diet with the following foods: peas. asparagus. sesame seeds. tuna. cheese. milk. eggs.
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