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How long does it take for bicalutamide to get out of your system? Some cases respond well to antiandrogen withdrawal, with a >50% decline in prostate-specific antigen (PSA) level, but the duration of remission is limited to approximately 6 months. We report here a patient with metastatic prostate cancer who had complete remission for almost 2 years after bicalutamide withdrawal. h7idag5g