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How common is minimal change disease? The short answer is that no one is sure. Minimal Change Disease is one of the most common causes of the Nephrotic Syndrome however, especially in children. In fact, almost 90% of children 10 and under with the Nephrotic Syndrome end up having MCD when biopsied (as opposed to 20% of adults). Can steroid injections cause kidney damage? Steroids caused a greater than expected increase in the risk of serious infections in the predominately young group of people who have immunoglobulin A (IgA) nephropathy, an immune disease that leads to kidney failure in almost a third of patients. How do you reduce swelling in nephrotic syndrome? Corticosteroids are a group of medications that reduce the activity of the immune system, decrease the amount of albumin lost in the urine, and decrease swelling. Health care providers commonly use prednisone or a related corticosteroid to treat idiopathic childhood nephrotic syndrome.
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