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Is Actonel safe to take? Actonel Warnings Actonel may cause serious jaw problems, especially if you have dental surgery or other dental treatments while taking the medicine. Actonel may cause severe bone, muscle, or joint pain. These symptoms may begin when you first start taking the drug, or after you've been using it for years. How long does it take for a Reclast infusion to work? On the day of the infusion, the administering nurse told us that it would take about 15 minutes, and we told her that the doctor had given specific instructions to administer it slowly over 60 minutes. What is pamidronate treatment used for? Pamidronate is used to treat high blood calcium levels and certain bone problems (bone metastases/lesions) that may occur with some types of cancer. It is also used to treat a certain type of bone disease (Paget's disease) that causes abnormal and weak bones.
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