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How long does it take for chemo to leave your body? Chemotherapy is out of your system a number of hours after you've had it given but the side effects can take up to about six months. During follow up you will be monitored to make sure that you are recovering from the chemotherapy. It is the overall effect on you and the body that takes more time.
Why does chemotherapy hurt so much? Bone pain - Due to bone damage from trauma or tumors, most likely. Chemotherapy or radiation induced pain - is most often a form of nerve pain. It can cause peripheral neuropathy (painful numbness of the extremities), or paresthesia (numbness and tingling of hands, feet or any extremity of the body).
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