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Why would metformin stop working? Why So Many People with Diabetes Stop Taking Metformin. Metformin works by reducing the amount of sugar released by the liver and improving how the body responds to insulin. It's been prescribed to more than 120 million people worldwide. The drug's lack of certain side effects compared to other medications are notable. Can you get diabetes if you're active? Anyone can get diabetes. However, you have a higher risk for diabetes if you are : Overweight. Inactive (exercise less than three times a week) What are the dangers of diabetes? Some of the potential complications of diabetes include: Heart and blood vessel disease. Diabetes dramatically increases the risk of heart disease, stroke, high blood pressure and narrowing of blood vessels (atherosclerosis). Nerve damage (neuropathy).
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