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Is diphenhydramine metabolized by the liver? Diphenhydramine undergoes extensive first-pass metabolism, whereby 50–60% of ingested medication is metabolized by the liver before reaching the systemic circulation. Nearly all the available drug is metabolized by the liver within 24–48 hours, thus increasing risk for liver injury.
What is the best herb for insomnia? The 6 Best Bedtime Teas That Help You Sleep Chamomile. For years, chamomile tea has been used as a natural remedy to reduce inflammation, decrease anxiety and treat insomnia. Valerian Root. Valerian is an herb that has been used for centuries to treat problems like insomnia, nervousness and headaches. Lavender. Lemon Balm. Passionflower. Magnolia Bark.
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