Can you have too much progesterone? There are no known serious medical consequences of having too much progesterone. However, the high progesterone levels are a consequence of and not a cause of this condition. Also, high levels of progesterone are associated with an increased risk for developing breast cancer. Can you take Prometrium in the morning? The 200 mg daily dosage of PROMETRIUM should be taken at bedtime. Patients receiving 300 mg PROMETRIUM daily should take one capsule (100 mg) in the morning and two capsules (200 mg) at bedtime. The morning dose should be taken 2 hours after breakfast. The toxicity of progesterone is very low.
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